Curcumin as an Anticancer Agent in Malignant Mesothelioma: A Review
نویسندگان
چکیده
منابع مشابه
Curcumin: a double hit on malignant mesothelioma.
Inflammation is a key mediator in the development of malignant mesothelioma, which has a dismal prognosis and poor therapeutic strategies. Curcumin, a naturally occurring polyphenol in turmeric, has been shown to possess anticarcinogenic properties through its anti-inflammatory effects. Inflammasomes, a component of inflammation, control the activation of caspase-1 leading to pyroptosis and pro...
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Rupseh Dudhe *, Pramod Kumar Sharma, Prabhakar Verma, Anshu Chaudhary a Department of Pharmaceutical Technology, Meerut Institute of Engineering & Technology, NH-58, Baghpat Bypass Crossing, Meerut (U. P.), India250005. Vishveshwarya Institute of Medical Science Dadri, Gautambudh Nagar (U.P.) India-203207. Uttarakhand Technical University, Dehradun (Uttarakhand), India248007. NIMS University, S...
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Primary malignant neoplasms of the pericardium are rare and are predominantly mesotheliomas, followed by benign localized fibrous mesothelioma, malignant fibrosarcoma, angiosarcoma and benign and malignant teratomas. 1 This article concerns an atypical presentation of this malignant tumor with symptoms and signs of pericardial effusion. This unusual feature was complete encasement of the h...
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The clinical benefits of curcumin as a single agent were demonstrated in patients with advanced pancreatic cancer in a phase 2 study despite pharmacokinetic analysis showing a much lower plasma concentration of curcumin in humans than in vitro. The diverse and broad biological activities of curcumin are mediated through direct interaction of curcumin with target proteins as well as epigenetic m...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2020
ISSN: 1422-0067
DOI: 10.3390/ijms21051839